GPR18 undergoes a high degree of constitutive trafficking but is unresponsive to N-Arachidonoyl Glycine

The orphan receptor GPR18 has become a research target following the discovery of a putative endogenous agonist, N-arachidonoyl glycine (NAGly). Chemical similarity between NAGly and the endocannabinoid anandamide suggested the hypothesis that GPR18 is a third cannabinoid receptor. GPR18-mediated ce...

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Bibliographic Details
Main Authors: David B. Finlay, Wayne R. Joseph, Natasha L. Grimsey, Michelle Glass
Format: Article
Language:English
Published: PeerJ Inc. 2016-03-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/1835.pdf