GPR18 undergoes a high degree of constitutive trafficking but is unresponsive to N-Arachidonoyl Glycine
The orphan receptor GPR18 has become a research target following the discovery of a putative endogenous agonist, N-arachidonoyl glycine (NAGly). Chemical similarity between NAGly and the endocannabinoid anandamide suggested the hypothesis that GPR18 is a third cannabinoid receptor. GPR18-mediated ce...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
PeerJ Inc.
2016-03-01
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Series: | PeerJ |
Subjects: | |
Online Access: | https://peerj.com/articles/1835.pdf |