A rat model of post-traumatic stress disorder reproduces the hippocampal deficits seen in the human syndrome

A rat model of post-traumatic stress disorder reproduces the hippocampal deficits seen in the human syndrome

Despite recent progress, the causes and pathophysiology of post-traumatic stress disorder (PTSD) remain poorly understood, partly because of ethical limitations inherent to human studies. One approach to circumvent this obstacle is to study PTSD in a valid animal model of the human syndrome. In one...

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Bibliographic Details
Main Authors: Sonal eGoswami, Sherin K Samuel, Olga eRodríguez Sierra, Michele eCascardi, Denis ePare
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-06-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
extinction
animal model
Post-traumatic stress disorder
recognition memory
predatory threat
elevated plus maze
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2012.00026/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnbeh.2012.00026/full

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