Wireless MRI‐Powered Reversible Orientation‐Locking Capsule Robot

Abstract Magnetic resonance imaging (MRI) scanners do not provide only high‐resolution medical imaging but also magnetic robot actuation and tracking. However, the rotational motion capabilities of MRI‐powered wireless magnetic capsule‐type robots have been limited due to the very high axial magneti...

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Main Authors: Onder Erin, Mustafa Boyvat, Jelena Lazovic, Mehmet Efe Tiryaki, Metin Sitti
Format: Article
Language:English
Published: Wiley 2021-07-01
Series:Advanced Science
Subjects:
Online Access:https://doi.org/10.1002/advs.202100463
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spelling doaj-043c950fed4940b1b637a186858460dd2021-07-07T08:04:26ZengWileyAdvanced Science2198-38442021-07-01813n/an/a10.1002/advs.202100463Wireless MRI‐Powered Reversible Orientation‐Locking Capsule RobotOnder Erin0Mustafa Boyvat1Jelena Lazovic2Mehmet Efe Tiryaki3Metin Sitti4Department of Physical Intelligence Max Planck Institute for Intelligent Systems Stuttgart 70569 GermanyDepartment of Physical Intelligence Max Planck Institute for Intelligent Systems Stuttgart 70569 GermanyDepartment of Physical Intelligence Max Planck Institute for Intelligent Systems Stuttgart 70569 GermanyDepartment of Physical Intelligence Max Planck Institute for Intelligent Systems Stuttgart 70569 GermanyDepartment of Physical Intelligence Max Planck Institute for Intelligent Systems Stuttgart 70569 GermanyAbstract Magnetic resonance imaging (MRI) scanners do not provide only high‐resolution medical imaging but also magnetic robot actuation and tracking. However, the rotational motion capabilities of MRI‐powered wireless magnetic capsule‐type robots have been limited due to the very high axial magnetic field inside the MRI scanner. Medical functionalities of such robots also remain a challenge due to the miniature robot designs. Therefore, a wireless capsule‐type reversible orientation‐locking robot (REVOLBOT) is proposed that has decoupled translational motion and planar orientation change capability by locking and unlocking the rotation of a spherical ferrous bead inside the robot on demand. Such an on‐demand locking/unlocking mechanism is achieved by a phase‐changing wax material in which the ferrous bead is embedded inside. Controlled and on‐demand hyperthermia and drug delivery using wireless power transfer‐based Joule heating induced by external alternating magnetic fields are the additional features of this robot. The experimental feasibility of the REVOLBOT prototype with steerable navigation, medical function, and MRI tracking capabilities with an 1.33 Hz scan rate is demonstrated inside a preclinical 7T small‐animal MRI scanner. The proposed robot has the potential for future clinical use in teleoperated minimally invasive treatment procedures with hyperthermia and drug delivery capabilities while being wirelessly powered and monitored inside MRI scanners.https://doi.org/10.1002/advs.202100463magnetic actuationmagnetic resonance imagingmedical robotsmillirobotsminimally invasive medical devices
collection DOAJ
language English
format Article
sources DOAJ
author Onder Erin
Mustafa Boyvat
Jelena Lazovic
Mehmet Efe Tiryaki
Metin Sitti
spellingShingle Onder Erin
Mustafa Boyvat
Jelena Lazovic
Mehmet Efe Tiryaki
Metin Sitti
Wireless MRI‐Powered Reversible Orientation‐Locking Capsule Robot
Advanced Science
magnetic actuation
magnetic resonance imaging
medical robots
millirobots
minimally invasive medical devices
author_facet Onder Erin
Mustafa Boyvat
Jelena Lazovic
Mehmet Efe Tiryaki
Metin Sitti
author_sort Onder Erin
title Wireless MRI‐Powered Reversible Orientation‐Locking Capsule Robot
title_short Wireless MRI‐Powered Reversible Orientation‐Locking Capsule Robot
title_full Wireless MRI‐Powered Reversible Orientation‐Locking Capsule Robot
title_fullStr Wireless MRI‐Powered Reversible Orientation‐Locking Capsule Robot
title_full_unstemmed Wireless MRI‐Powered Reversible Orientation‐Locking Capsule Robot
title_sort wireless mri‐powered reversible orientation‐locking capsule robot
publisher Wiley
series Advanced Science
issn 2198-3844
publishDate 2021-07-01
description Abstract Magnetic resonance imaging (MRI) scanners do not provide only high‐resolution medical imaging but also magnetic robot actuation and tracking. However, the rotational motion capabilities of MRI‐powered wireless magnetic capsule‐type robots have been limited due to the very high axial magnetic field inside the MRI scanner. Medical functionalities of such robots also remain a challenge due to the miniature robot designs. Therefore, a wireless capsule‐type reversible orientation‐locking robot (REVOLBOT) is proposed that has decoupled translational motion and planar orientation change capability by locking and unlocking the rotation of a spherical ferrous bead inside the robot on demand. Such an on‐demand locking/unlocking mechanism is achieved by a phase‐changing wax material in which the ferrous bead is embedded inside. Controlled and on‐demand hyperthermia and drug delivery using wireless power transfer‐based Joule heating induced by external alternating magnetic fields are the additional features of this robot. The experimental feasibility of the REVOLBOT prototype with steerable navigation, medical function, and MRI tracking capabilities with an 1.33 Hz scan rate is demonstrated inside a preclinical 7T small‐animal MRI scanner. The proposed robot has the potential for future clinical use in teleoperated minimally invasive treatment procedures with hyperthermia and drug delivery capabilities while being wirelessly powered and monitored inside MRI scanners.
topic magnetic actuation
magnetic resonance imaging
medical robots
millirobots
minimally invasive medical devices
url https://doi.org/10.1002/advs.202100463
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