Genomic analysis reveals a potential role for cell cycle perturbation in HCV-mediated apoptosis of cultured hepatocytes.

The mechanisms of liver injury associated with chronic HCV infection, as well as the individual roles of both viral and host factors, are not clearly defined. However, it is becoming increasingly clear that direct cytopathic effects, in addition to immune-mediated processes, play an important role i...

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Bibliographic Details
Main Authors: Kathie-Anne Walters, Andrew J Syder, Sharon L Lederer, Deborah L Diamond, Bryan Paeper, Charles M Rice, Michael G Katze
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2613535?pdf=render