Myxofibrosarcoma harboring an MLH1 pathogenic germline variant associated with Muir-Torre syndrome: a case report

Myxofibrosarcoma harboring an MLH1 pathogenic germline variant associated with Muir-Torre syndrome: a case report

Abstract Background Muir–Torre syndrome (MTS), which accounts for a small subset (1–3 %) of Lynch syndrome (LS), is an autosomal dominant genetic disorder characterized by sebaceous gland or keratoacanthoma associated with visceral malignancies. Most families with MTS have pathogenic germline varian...

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Bibliographic Details
Main Authors: Makoto Nakagawa, Eisuke Kobayashi, Masayoshi Yamada, Tomoko Watanabe, Makoto Hirata, Noriko Tanabe, Mineko Ushiama, Hiromi Sakamoto, Chiaki Sato, Taisuke Mori, Akihiko Yoshida, Teruhiko Yoshida, Kokichi Sugano, Akira Kawai
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Hereditary Cancer in Clinical Practice
Subjects:
Myxofibrosarcoma
Muir-Torre syndrome
Lynch syndrome
Mismatch repair (MMR)
Microsatellite instability (MSI)
Online Access:https://doi.org/10.1186/s13053-021-00192-z

Internet

https://doi.org/10.1186/s13053-021-00192-z

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