Effect of neutrophil depletion on gelatinase expression, edema formation and hemorrhagic transformation after focal ischemic stroke

<p>Abstract</p> <p>Background</p> <p>While gelatinase (MMP-2 and -9) activity is increased after focal ischemia/reperfusion injury in the brain, the relative contribution of neutrophils to the MMP activity and to the development of hemorrhagic transformation remains unk...

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Bibliographic Details
Main Authors: Machado Livia S, Kozak Anna, Ergul Adviye, Harris Alex K, Johnson Maribeth H, Fagan Susan C
Format: Article
Language:English
Published: BMC 2005-08-01
Series:BMC Neuroscience
Online Access:http://www.biomedcentral.com/1471-2202/6/49