Protection against bronchiolitis obliterans syndrome is associated with allograft CCR7+ CD45RA- T regulatory cells.

Bronchiolitis obliterans syndrome (BOS) is the major obstacle to long-term survival after lung transplantation, yet markers for early detection and intervention are currently lacking. Given the role of regulatory T cells (Treg) in modulation of immunity, we hypothesized that frequencies of Treg in b...

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Main Authors: Aric L Gregson, Aki Hoji, Vyacheslav Palchevskiy, Scott Hu, S Samuel Weigt, Eileen Liao, Ariss Derhovanessian, Rajeev Saggar, Sophie Song, Robert Elashoff, Otto O Yang, John A Belperio
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-06-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2894051?pdf=render