Exploring the Functional Complementation between Grp94 and Hsp90.

Grp94 and Hsp90 are the ER and cytoplasmic paralog members, respectively, of the hsp90 family of molecular chaperones. The structural and biochemical differences between Hsp90 and Grp94 that allow each paralog to efficiently chaperone its particular set of clients are poorly understood. The two para...

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Bibliographic Details
Main Authors: Kevin A Maharaj, Nanette L S Que, Feng Hong, John D Huck, Sabrina K Gill, Shuang Wu, Zihai Li, Daniel T Gewirth
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5100913?pdf=render