The LetA/S two-component system regulates transcriptomic changes that are essential for the culturability of Legionella pneumophila in water

Abstract Surviving the nutrient-poor aquatic environment for extended periods of time is important for the transmission of various water-borne pathogens, including Legionella pneumophila (Lp). Previous work concluded that the stringent response and the sigma factor RpoS are essential for the surviva...

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Bibliographic Details
Main Authors: Nilmini Mendis, Peter McBride, Joseph Saoud, Thangadurai Mani, Sebastien P. Faucher
Format: Article
Language:English
Published: Nature Publishing Group 2018-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-24263-9