Osteoinductive 3D printed scaffold healed 5 cm segmental bone defects in the ovine metatarsus

Abstract Autologous bone grafts are considered the gold standard grafting material for the treatment of nonunion, but in very large bone defects, traditional autograft alone is insufficient to induce repair. Recombinant human bone morphogenetic protein 2 (rhBMP-2) can stimulate bone regeneration and...

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Bibliographic Details
Main Authors: Yunzhi Peter Yang, Kevin M. Labus, Benjamin C. Gadomski, Arnaud Bruyas, Jeremiah Easley, Brad Nelson, Ross H. Palmer, Kirk McGilvray, Daniel Regan, Christian M. Puttlitz, Alexander Stahl, Elaine Lui, Jiannan Li, Seyedsina Moeinzadeh, Sungwoo Kim, William Maloney, Michael J. Gardner
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-86210-5