Application of enhanced electronegative multimodal chromatography as the primary capture step for immunoglobulin G purification

Application of enhanced electronegative multimodal chromatography as the primary capture step for immunoglobulin G purification

Abstract In recent studies, electronegative multimodal chromatography with Eshmuno HCX was demonstrated to be a highly promising recovery step for direct immunoglobulin G (IgG) capture from undiluted cell culture fluid. In this study, the binding properties of HCX to IgG at different pH/salt combina...

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Bibliographic Details
Main Authors: Yanli Wang, Quan Chen, Mo Xian, Rui Nian, Fei Xu
Format: Article
Language:English
Published: SpringerOpen 2018-06-01
Series:AMB Express
Subjects:
Monoclonal antibody
Electronegative multimodal
Non-affinity purification
Cost-savings
Online Access:http://link.springer.com/article/10.1186/s13568-018-0622-3

Internet

http://link.springer.com/article/10.1186/s13568-018-0622-3

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