Characterization of ornidazole metabolites in human bile after intraveneous doses by ultraperformance liquid chromatography/quadrupole time-of-flight mass spectrometry

Characterization of ornidazole metabolites in human bile after intraveneous doses by ultraperformance liquid chromatography/quadrupole time-of-flight mass spectrometry

Ultraperformance liquid chromatography/quadrupole time-of-flight mass spectrometry (UPLC/Q-TOF MS) was used to characterize ornidazole metabolites in human bile after intravenous doses. A liquid chromatography tandem mass spectrometry (LC–MS/MS) assay was developed for the determination of the bile...

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Bibliographic Details
Main Authors: Jiangbo Du, Pan Deng, Xiaoyan Chen, Haidong Wang, Tiangeng You, Dafang Zhong
Format: Article
Language:English
Published: Elsevier 2012-04-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Ornidazole
UPLC/Q-TOF MS
LC–MS/MS
Human bile
Metabolite
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383512000159

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http://www.sciencedirect.com/science/article/pii/S2211383512000159

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