S-Adenosylmethionine regulates apoptosis and autophagy in MCF-7 breast cancer cells through the modulation of specific microRNAs

S-Adenosylmethionine regulates apoptosis and autophagy in MCF-7 breast cancer cells through the modulation of specific microRNAs

Abstract Background To get insight into the molecular mechanisms underlying the anti-tumor activity of S-adenosyl-l-methionine (AdoMet), we analyzed AdoMet-induced modulation of microRNAs (miRNAs) expression profile in MCF-7 breast cell line and its correlation with cancer-related biological pathway...

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Bibliographic Details
Main Authors: Concetta Paola Ilisso, Donatella Delle Cave, Laura Mosca, Martina Pagano, Alessandra Coppola, Luigi Mele, Michele Caraglia, Giovanna Cacciapuoti, Marina Porcelli
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Cancer Cell International
Subjects:
S-Adenosylmethionine
Breast cancer cells
Apoptosis
Autophagy
MicroRNA
Online Access:http://link.springer.com/article/10.1186/s12935-018-0697-6

Internet

http://link.springer.com/article/10.1186/s12935-018-0697-6

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