Comparison of two voltage-sensitive dyes and their suitability for long-term imaging of neuronal activity.

One of the key approaches for studying neural network function is the simultaneous measurement of the activity of many neurons. Voltage-sensitive dyes (VSDs) simultaneously report the membrane potential of multiple neurons, but often have pharmacological and phototoxic effects on neuronal cells. Yet...

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Bibliographic Details
Main Authors: Stephanie Preuss, Wolfgang Stein
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3790875?pdf=render