Microwave versus conventional synthesis, anticancer, DNA binding and docking studies of some 1,2,3-triazoles carrying benzothiazole

Microwave versus conventional synthesis, anticancer, DNA binding and docking studies of some 1,2,3-triazoles carrying benzothiazole

The present work describes the synthesis of new click products with a 2-mercapto-benzothiazole basic structure supporting the different functionalized side chains linked to the 1,2,3-triazole ring at position N-1 via Cu(I)-mediated click chemistry under both thermal and microwave irradiation (MWI)....

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Bibliographic Details
Main Authors: Ateyatallah Aljuhani, Meshal A. Almehmadi, Ibrahim O. Barnawi, Nadjet Rezki, Imran Ali, Mouslim Messali, Mohamed Reda Aouad
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Arabian Journal of Chemistry
Subjects:
Synthesis of benzothiazole
1,2,3-triazole
Molecular hybridization
Anticancer activities
DNA binding
DNA docking
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535221000125

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http://www.sciencedirect.com/science/article/pii/S1878535221000125

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