Reliability of a Novel Model for Drug Release from 2D HPMC-Matrices

A novel model of drug release from 2D-HPMC matrices is considered. Detailed mathematical description of matrix swelling and the effect of the initial drug loading are introduced. A numerical approach to solution of the posed nonlinear 2D problem is used on the basis of finite element domain approxim...

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Bibliographic Details
Main Authors: Rumiana Blagoeva, Assen Nedev
Format: Article
Language:English
Published: Bulgarian Academy of Sciences 2010-04-01
Series:International Journal Bioautomation
Subjects:
Online Access:http://www.clbme.bas.bg/bioautomation/2010/vol_14.1/files/14.1_03.pdf