A genome-wide scan reveals important roles of DNA methylation in human longevity by regulating age-related disease genes.

It is recognized that genetic factors contribute to human longevity. Besides the hypothesis of existence of longevity genes, another suggests that a lower frequency of risk alleles decreases the incidence of age-related diseases in the long-lived people. However, the latter finds no support from rec...

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Bibliographic Details
Main Authors: Fu-Hui Xiao, Yong-Han He, Qi-Gang Li, Huan Wu, Long-Hai Luo, Qing-Peng Kong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4368809?pdf=render