Genetic Deletion of NOD1 Prevents Cardiac Ca<sup>2+</sup> Mishandling Induced by Experimental Chronic Kidney Disease

Genetic Deletion of NOD1 Prevents Cardiac Ca<sup>2+</sup> Mishandling Induced by Experimental Chronic Kidney Disease

Risk of cardiovascular disease (CVD) increases considerably as renal function declines in chronic kidney disease (CKD). Nucleotide-binding oligomerization domain-containing protein 1 (NOD1) has emerged as a novel innate immune receptor involved in both CVD and CKD. Following activation, NOD1 undergo...

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Bibliographic Details
Main Authors: Marta Gil-Fernández, José Alberto Navarro-García, Almudena Val-Blasco, Laura González-Lafuente, José Carlos Martínez, Angélica Rueda, Maria Tamayo, José Luis Morgado, Carlos Zaragoza, Luis Miguel Ruilope, Carmen Delgado, Gema Ruiz-Hurtado, María Fernández-Velasco
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:International Journal of Molecular Sciences
Subjects:
NOD1
chronic kidney disease
RIP2
RyR<sub>2</sub>
Ca<sup>2+</sup> handling
Online Access:https://www.mdpi.com/1422-0067/21/22/8868

Internet

https://www.mdpi.com/1422-0067/21/22/8868

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