Ultrastructural and Molecular Analyses Reveal Enhanced Nucleolar Activity in Medicago truncatula Cells Overexpressing the MtTdp2α Gene

Ultrastructural and Molecular Analyses Reveal Enhanced Nucleolar Activity in Medicago truncatula Cells Overexpressing the MtTdp2α Gene

The role of tyrosyl-DNA phosphodiesterase 2 (Tdp2) involved in the repair of 5′-end-blocking DNA lesions is still poorly explored in plants. To gain novel insights, Medicago truncatula suspension cultures overexpressing the MtTdp2α gene (Tdp2α-13C and Tdp2α-28 lines, respectively) and a control (CTR...

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Bibliographic Details
Main Authors: Anca Macovei, Matteo Faè, Marco Biggiogera, Susana de Sousa Araújo, Daniela Carbonera, Alma Balestrazzi
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Plant Science
Subjects:
etoposide
Medicago truncatula
nucleolus
transmission electron microscopy
tyrosyl-DNA phosphodiesterase
Online Access:http://journal.frontiersin.org/article/10.3389/fpls.2018.00596/full

Internet

http://journal.frontiersin.org/article/10.3389/fpls.2018.00596/full

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