The Research of G–Motif Construction and Chirality in Deoxyguanosine Monophosphate Nucleotide Complexes

The Research of G–Motif Construction and Chirality in Deoxyguanosine Monophosphate Nucleotide Complexes

A detailed understanding of the mismatched base-pairing interactions in DNA will help reveal genetic diseases and provide a theoretical basis for the development of targeted drugs. Here, we utilized mononucleotide fragment to simulate mismatch DNA interactions in a local hydrophobic microenvironment...

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Bibliographic Details
Main Authors: Yanhong Zhu, Zhongkui Li, Pengfei Wang, Qi–Ming Qiu, Hongwei Ma, Hui Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Chemistry
Subjects:
base-pair mismatch
g–motif
self-assembly
chirality
crystal structure
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2021.709777/full

Internet

https://www.frontiersin.org/articles/10.3389/fchem.2021.709777/full

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