Development of the method of trifluoroacetates determination in glatiramer acetate pharmaceutical substance by<sup>19</sup>F NMR spectroscopy

Development of the method of trifluoroacetates determination in glatiramer acetate pharmaceutical substance by<sup>19</sup>F NMR spectroscopy

The article describes a newly developed procedure of quantitative determination of fluorine which is present in residual trifluoroacetates in glatiramer acetate pharmaceutical substances by19F NMR spectroscopy. Test parameters (the relaxation delay and the number of scans) were selected to minimize...

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Bibliographic Details
Main Authors: S. V. Moiseev, V. I. Krylov, N. E. Kuz’Mina, V. A. Yashkir, V. A. Merkulov
Format: Article
Language:Russian
Published: OOO “Vashe Tsifrovoe Izdatelstvo” 2018-02-01
Series:Ведомости Научного центра экспертизы средств медицинского применения
Subjects:
глатирамера ацетат
метод<sup>19</sup>f ямр-спектроскопии
количественное определение
внутренний стандарт
трифторуксусная кислота
glatiramer acetate
<sup>19</sup>f nmr spectroscopy
quantitation
internal standard
trifluoroacetic acid
Online Access:https://www.vedomostincesmp.ru/jour/article/view/149

Internet

https://www.vedomostincesmp.ru/jour/article/view/149

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