Bilirubin Promotes De Novo Generation of T Regulatory Cells
We have previously demonstrated that bilirubin administration to the recipient induces tolerance towards islet cell transplants across a complete MHC mismatch in a mouse model. Here we assess the mechanisms of such protection. Bilirubin treatment of recipients improved function of islet allografts b...
Main Authors: | Fredy Rocuts, Xinyu Zhang, Jun Yan, Yinan Yue, Michael Thomas, Fritz H. Bach, Eva Czismadia, Hongjun Wang Ph.D. |
---|---|
Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2010-04-01
|
Series: | Cell Transplantation |
Online Access: | https://doi.org/10.3727/096368909X484680 |
Similar Items
-
Activation of Peroxisome Proliferator-Activated Receptor γ Prolongs Islet Allograft Survival
by: Hongjun Wang Ph.D., et al.
Published: (2012-10-01) -
Trichostatin A Promotes the Generation and Suppressive Functions of Regulatory T Cells
by: Cristian Doñas, et al.
Published: (2013-01-01) -
Protective effects of serum bilirubin on peripheral vascular disease
by: Libor Vítek, M.D., PhD, MBA, et al.
Published: (2008-01-01) -
Substantial Effect of Efavirenz Monotherapy on Bilirubin Levels in Healthy Volunteers
by: Ingrid F. Metzger, PhD, et al.
Published: (2014-12-01) -
Role of Bilirubin in Diabetic Vascular Complications: Can Bilirubin Predict More than Just Liver Disease?
by: Jun Sung Moon
Published: (2015-10-01)