Bilirubin Promotes De Novo Generation of T Regulatory Cells

We have previously demonstrated that bilirubin administration to the recipient induces tolerance towards islet cell transplants across a complete MHC mismatch in a mouse model. Here we assess the mechanisms of such protection. Bilirubin treatment of recipients improved function of islet allografts b...

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Bibliographic Details
Main Authors: Fredy Rocuts, Xinyu Zhang, Jun Yan, Yinan Yue, Michael Thomas, Fritz H. Bach, Eva Czismadia, Hongjun Wang Ph.D.
Format: Article
Language:English
Published: SAGE Publishing 2010-04-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368909X484680