Heme oxygenase-1 prevents heart against myocardial infarction by attenuating ischemic injury-induced cardiomyocytes senescenceResearch in context

Background: Cellular senescence is a stable cell-cycle arrest induced by telomere shortening and various types of cellular stress including oxidative stress, oncogene activation, DNA damage etc. Heme oxygenase-1 (HO-1) is an inducible stress-response protein that plays antioxidant and anti-apoptotic...

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Bibliographic Details
Main Authors: Huitong Shan, Tianyu Li, Lijia Zhang, Rui Yang, Yue Li, Mingyu Zhang, Yuechao Dong, Yuhong Zhou, Chaoqian Xu, Baofeng Yang, Haihai Liang, Xu Gao, Hongli Shan
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396418305607