The Mitochondrial Ca<sup>2+</sup> Overload via Voltage-Gated Ca<sup>2+</sup> Entry Contributes to an Anti-Melanoma Effect of Diallyl Trisulfide

The Mitochondrial Ca<sup>2+</sup> Overload via Voltage-Gated Ca<sup>2+</sup> Entry Contributes to an Anti-Melanoma Effect of Diallyl Trisulfide

<i>Allium</i> vegetables such as garlic (<i>Allium sativum</i> L.) are rich in organosulfur compounds that prevent human chronic diseases, including cancer. Of these, diallyl trisulfide (DATS) exhibits anticancer effects against a variety of tumors, including malignant melano...

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Bibliographic Details
Main Authors: Chinatsu Nakagawa, Manami Suzuki-Karasaki, Miki Suzuki-Karasaki, Toyoko Ochiai, Yoshihiro Suzuki-Karasaki
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:International Journal of Molecular Sciences
Subjects:
diallyl trisulfide
melittin
melanoma
apoptosis
mitochondrial ca<sup>2+</sup>
store-operated ca<sup>2+</sup> channel
acidification
ca<sup>2+</sup> channel blocker
voltage-gated ca<sup>2+</sup> channel
Online Access:https://www.mdpi.com/1422-0067/21/2/491

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https://www.mdpi.com/1422-0067/21/2/491

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