Fucoidan Elevates MicroRNA-29b to Regulate DNMT3B-MTSS1 Axis and Inhibit EMT in Human Hepatocellular Carcinoma Cells

Fucoidan Elevates MicroRNA-29b to Regulate DNMT3B-MTSS1 Axis and Inhibit EMT in Human Hepatocellular Carcinoma Cells

Accumulating evidence has revealed that fucoidan exhibits anti-tumor activities by arresting cell cycle and inducing apoptosis in many types of cancer cells including hepatocellular carcinoma (HCC). Exploring its effect on microRNA expression, we found that fucoidan markedly upregulated miR-29b of h...

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Bibliographic Details
Main Authors: Ming-De Yan, Chih-Jung Yao, Jyh-Ming Chow, Chia-Lun Chang, Pai-An Hwang, Shuang-En Chuang, Jacqueline Whang-Peng, Gi-Ming Lai
Format: Article
Language:English
Published: MDPI AG 2015-09-01
Series:Marine Drugs
Subjects:
fucoidan
hepatocellular carcinoma
miR-29b
DNMT3B
MTSS1
EMT
Online Access:http://www.mdpi.com/1660-3397/13/10/6099

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http://www.mdpi.com/1660-3397/13/10/6099

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