Specificity Characterization of SLA Class I Molecules Binding to Swine-Origin Viral Cytotoxic T Lymphocyte Epitope Peptides in Vitro

Specificity Characterization of SLA Class I Molecules Binding to Swine-Origin Viral Cytotoxic T Lymphocyte Epitope Peptides in Vitro

Swine leukocyte antigen (SLA) class I molecules play a crucial role in generating specific cellular immune responses against viruses and other intracellular pathogens. They mainly bind and present antigens of intracellular origin to circulating MHC I-restricted cytotoxic T lymphocytes (CTLs). Bindin...

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Bibliographic Details
Main Authors: Caixia Gao, Xiwen He, Jinqiang Quan, Qian Jiang, Huan Lin, Hongyan Chen, Liandong Qu
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-12-01
Series:Frontiers in Microbiology
Subjects:
swine leukocyte antigen
major histocompatibility complex
CTL epitope peptide
specific binding
MHC restriction
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2017.02524/full

Internet

http://journal.frontiersin.org/article/10.3389/fmicb.2017.02524/full

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