Probing the subcellular nanostructure of engineered human cardiomyocytes in 3D tissue

Abstract The structural and functional maturation of human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) is essential for pharmaceutical testing, disease modeling, and ultimately therapeutic use. Multicellular 3D-tissue platforms have improved the functional maturation of hiPSC-CM...

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Bibliographic Details
Main Authors: Josh Javor, Jourdan K. Ewoldt, Paige E. Cloonan, Anant Chopra, Rebeccah J. Luu, Guillaume Freychet, Mikhail Zhernenkov, Karl Ludwig, Jonathan G. Seidman, Christine E. Seidman, Christopher S. Chen, David J. Bishop
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Microsystems & Nanoengineering
Online Access:https://doi.org/10.1038/s41378-020-00234-x