Cell surface expression and function of the macromolecular C1 complex on the surface of human monocytes

Cell surface expression and function of the macromolecular C1 complex on the surface of human monocytes

The synthesis of the subunits of the C1 complex (C1q, C1s, C1r), and its regulator C1 inhibitor (C1-Inh) by human monocytes has been previously established. However, surface expression of these molecules by monocytes has not been shown. Using flow cytometry and antigen-capture ELISA, we show here fo...

Full description

Bibliographic Details
Main Authors: Kinga K Hosszu, Alisa eValentino, Yan eJi, Mara eMatkovic, Lina ePednekar, Nina eRehage, Nithin eTumma, Ellinor I.E. Peerschke, Berhane eGhebrehiwet
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-03-01
Series:Frontiers in Immunology
Subjects:
Monocytes
U937 Cells
immunology
complement
C1 complex
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00038/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00038/full

Similar Items