Predicting MHC I restricted T cell epitopes in mice with NAP-CNB, a novel online tool

Abstract Lack of a dedicated integrated pipeline for neoantigen discovery in mice hinders cancer immunotherapy research. Novel sequential approaches through recurrent neural networks can improve the accuracy of T-cell epitope binding affinity predictions in mice, and a simplified variant selection p...

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Bibliographic Details
Main Authors: Carlos Wert-Carvajal, Rubén Sánchez-García, José R Macías, Rebeca Sanz-Pamplona, Almudena Méndez Pérez, Ramon Alemany, Esteban Veiga, Carlos Óscar S. Sorzano, Arrate Muñoz-Barrutia
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-89927-5