Chemical modification of proteins by insertion of synthetic peptides using tandem protein trans-splicing

Chemical modification of proteins can be used to decipher function or use that function for therapeutic purposes. Here, the authors insert synthetic peptides via tandem protein trans-splicing to add post-translational modifications or non-canonical amino acids.

Bibliographic Details
Main Authors: K. K. Khoo, I. Galleano, F. Gasparri, R. Wieneke, H. Harms, M. H. Poulsen, H. C. Chua, M. Wulf, R. Tampé, S. A. Pless
Format: Article
Language:English
Published: Nature Publishing Group 2020-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-16208-6