The transcriptomic and epigenetic map of vascular quiescence in the continuous lung endothelium

The transcriptomic and epigenetic map of vascular quiescence in the continuous lung endothelium

Maintenance of a quiescent and organotypically-differentiated layer of blood vessel-lining endothelial cells (EC) is vital for human health. Yet, the molecular mechanisms of vascular quiescence remain largely elusive. Here we identify the genome-wide transcriptomic program controlling the acquisitio...

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Bibliographic Details
Main Authors: Katharina Schlereth, Dieter Weichenhan, Tobias Bauer, Tina Heumann, Evangelia Giannakouri, Daniel Lipka, Samira Jaeger, Matthias Schlesner, Patrick Aloy, Roland Eils, Christoph Plass, Hellmut G Augustin
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-05-01
Series:eLife
Subjects:
endothelial quiescence
endothelial trsanscriptome
endothelial epigenome
DNA methylation
TGFß
Online Access:https://elifesciences.org/articles/34423

Internet

https://elifesciences.org/articles/34423

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