Characterisation of genome-wide PLZF/RARA target genes.

The PLZF/RARA fusion protein generated by the t(11;17)(q23;q21) translocation in acute promyelocytic leukaemia (APL) is believed to act as an oncogenic transcriptional regulator recruiting epigenetic factors to genes important for its transforming potential. However, molecular mechanisms associated...

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Bibliographic Details
Main Authors: Salvatore Spicuglia, Christelle Vincent-Fabert, Touati Benoukraf, Guillaume Tibéri, Andrew J Saurin, Joaquin Zacarias-Cabeza, David Grimwade, Ken Mills, Boris Calmels, François Bertucci, Michael Sieweke, Pierre Ferrier, Estelle Duprez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21949697/?tool=EBI