Identification of a First Human Norovirus CD8+ T Cell Epitope Restricted to HLA-A*0201 Allele

Norovirus (NoV) causes a substantial global burden of acute gastroenteritis in all age groups and the development of NoV vaccine is a high priority. There are still gaps in understanding of protective NoV-specific immunity. Antibody mediated immune responses have been widely studied, but in contrast...

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Bibliographic Details
Main Authors: Maria Malm, Timo Vesikari, Vesna Blazevic
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02782/full