Development and Validation of a CD8+ T Cell Infiltration-Related Signature for Melanoma Patients

Development and Validation of a CD8+ T Cell Infiltration-Related Signature for Melanoma Patients

AimImmunotherapy shows efficacy in only a subset of melanoma patients. Here, we intended to construct a risk score model to predict melanoma patients’ sensitivity to immunotherapy.MethodsIntegration analyses were performed on melanoma patients from high-dimensional public datasets. The CD8+ T cell i...

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Bibliographic Details
Main Authors: Yuan Yuan, Zheng Zhu, Ying Lan, Saili Duan, Ziqing Zhu, Xi Zhang, Guoyin Li, Hui Qu, Yanhui Feng, Hui Cai, Zewen Song
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Immunology
Subjects:
CD8+ T cells
melanoma
single cell RNA sequencing analysis
immunotherapy
immune response
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.659444/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.659444/full

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