Targeted Delivery of siRNA

Therapeutic application of siRNA requires delivery to the correct intracellular location, to interact with the RNAi machinery within the target cell, within the target tissue responsible for the pathology. Each of these levels of targeting poses a significant barrier. To overcome these barriers seve...

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Bibliographic Details
Main Authors: Sabrina Oliveira, Gert Storm, Raymond M. Schiffelers
Format: Article
Language:English
Published: Hindawi Limited 2006-01-01
Series:Journal of Biomedicine and Biotechnology
Online Access:http://dx.doi.org/10.1155/JBB/2006/63675