Extracellular matrix fragmentation in young, healthy cartilaginous tissues

Although the composition and structure of cartilaginous tissues is complex, collagen II fibrils and aggrecan are the most abundant assemblies in both articular cartilage (AC) and the nucleus pulposus (NP) of the intervertebral disc (IVD). Whilst structural heterogeneity of intact aggrecan ( containi...

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Bibliographic Details
Main Authors: RJ Craddock, NW Hodson, M Ozols, T Shearer, JA Hoyland, MJ Sherratt
Format: Article
Language:English
Published: AO Research Institute Davos 2018-02-01
Series:European Cells & Materials
Subjects:
Online Access:http://www.ecmjournal.org/papers/vol035/pdf/v035a04.pdf