Human umbilical cord mesenchymal stem cells restore the ovarian metabolome and rescue premature ovarian insufficiency in mice

Human umbilical cord mesenchymal stem cells restore the ovarian metabolome and rescue premature ovarian insufficiency in mice

Abstract Background Premature ovarian insufficiency (POI) is an ovarian dysfunction that seriously affects a woman’s physiological health and reproduction. Mesenchymal stem cell (MSC) transplantation offers a promising treatment option for ovarian restoration in rodent POI models. However, the effic...

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Bibliographic Details
Main Authors: Yan Zhao, Jiao Ma, Peiye Yi, Jun Wu, Feiyan Zhao, Wan Tu, Wenjing Liu, Tianda Li, Yan Deng, Jie Hao, Hongmei Wang, Long Yan
Format: Article
Language:English
Published: BMC 2020-11-01
Series:Stem Cell Research & Therapy
Subjects:
Ovarian function restoration
Premature ovarian insufficiency
Mesenchymal stem cell
Metabolomics
Metabolite
Online Access:http://link.springer.com/article/10.1186/s13287-020-01972-5

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http://link.springer.com/article/10.1186/s13287-020-01972-5

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