Relationship between mitochondrial electron transport chain dysfunction, development, and life extension in Caenorhabditis elegans.
Prior studies have shown that disruption of mitochondrial electron transport chain (ETC) function in the nematode Caenorhabditis elegans can result in life extension. Counter to these findings, many mutations that disrupt ETC function in humans are known to be pathologically life-shortening. In this...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2007-10-01
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| Series: | PLoS Biology |
| Online Access: | http://europepmc.org/articles/PMC1994989?pdf=render |