Plasma concentrations and placental immunostaining of interleukin-10 and tumornecrosis factor-α as predictors of alterations in the embryo-fetal organism and the placental development of diabetic rats

Interleukin-10 (IL-10) appears to be the key cytokine for the maintenance of pregnancy and inhibits the secretion of inflammatory cytokines such as tumor necrosis factor-α (TNF-α). However, there are no studies evaluating the profile of these cytokines in diabetic rat models. Thus, our aim was to an...

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Bibliographic Details
Main Authors: Y.K. Sinzato, D.C. Damasceno, R. Laufer-Amorim, M.M.P. Rodrigues, M. Oshiiwa, K.N. Taylor, M.V.C. Rudge
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2011-03-01
Series:Brazilian Journal of Medical and Biological Research
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2011000300005&lng=en&tlng=en