An X chromosome association scan of the Norfolk Island genetic isolate provides evidence for a novel migraine susceptibility locus at Xq12.

Migraine is a common and debilitating neurovascular disorder with a complex envirogenomic aetiology. Numerous studies have demonstrated a preponderance of women affected with migraine and previous pedigree linkage studies in our laboratory have identified susceptibility loci on chromosome Xq24-Xq28....

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Main Authors: Bridget H Maher, Rod A Lea, Miles Benton, Hannah C Cox, Claire Bellis, Melanie Carless, Thomas D Dyer, Joanne Curran, Jac C Charlesworth, Julie E Buring, Tobias Kurth, Daniel I Chasman, Paul M Ridker, Markus Schürks, John Blangero, Lyn R Griffiths
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3362572?pdf=render