Hysteresis and bistability in the succinate-CoQ reductase activity and reactive oxygen species production in the mitochondrial respiratory complex II

Hysteresis and bistability in the succinate-CoQ reductase activity and reactive oxygen species production in the mitochondrial respiratory complex II

The mitochondrial respiratory Complex II (CII) is one of key enzymes of cell energy metabolism, linking the tricarboxylic acid (TCA) cycle and the electron transport chain (ETC). CII reversibly oxidizes succinate to fumarate in the TCA cycle and transfers the electrons, produced by this reaction to...

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Bibliographic Details
Main Authors: Nikolay I. Markevich, Miliausha H. Galimova, Lubov N. Markevich
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:Redox Biology
Subjects:
Complex II
Reactive oxygen species (ROS)
Computational model
Hysteresis
Bistability
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231720308351

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http://www.sciencedirect.com/science/article/pii/S2213231720308351

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