Rapid Discrimination of Chlorpheniramine Maleate and Assessment of Its Surface Content Uniformity in a Pharmaceutical Formulation by NIR-CI Coupled with Statistical Measurement

This study demonstrated that near infrared chemical imaging (NIR-CI) was a rapid and nondestructive technique for discrimination of chlorpheniramine maleate (CPM) and assessment of its surface content uniformity (SCU) in a pharmaceutical formulation. The characteristic wavenumber method was used for...

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Bibliographic Details
Main Authors: Luwei Zhou, Zhisheng Wu, Xinyuan Shi, Manfei Xu, Xiaona Liu, Bing Xu, Yanjiang Qiao
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:Journal of Spectroscopy
Online Access:http://dx.doi.org/10.1155/2014/741246