The PCNA unloader Elg1 promotes recombination at collapsed replication forks in fission yeast
Protein-DNA complexes can impede DNA replication and cause replication fork collapse. Whilst it is known that homologous recombination is deployed in such instances to restart replication, it is unclear how a stalled fork transitions into a collapsed fork at which recombination proteins can load. Pr...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2019-05-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/47277 |