Genetic Markers and Danger Signals in Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis

Genetic Markers and Danger Signals in Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis

Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening adverse reactions, which could be induced by a variety of drugs. It was proposed that human leukocyte antigen (HLA)-restricted presentation of antigens (drugs or their metabolites) to T lymphocytes initiates the...

Full description

Bibliographic Details
Main Authors: Wen-Hung Chung, Shuen-Iu Hung
Format: Article
Language:English
Published: Elsevier 2010-01-01
Series:Allergology International
Subjects:
drug hypersensitivity
genetic polymorphism
NK cells
Stevens-Johnson syndrome
toxic epidermal necrolysis
Online Access:http://www.sciencedirect.com/science/article/pii/S1323893015306432

Internet

http://www.sciencedirect.com/science/article/pii/S1323893015306432

Similar Items