BTN2A2 protein negatively regulates T cells to ameliorate collagen-induced arthritis in mice

Abstract Rheumatoid arthritis (RA) is an autoimmune disorder characterized by persistent inflammatory responses in target tissues and organs, resulting in the destruction of joints. Collagen type II (CII)-induced arthritis (CIA) is the most used animal model for human RA. Although BTN2A2 protein has...

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Bibliographic Details
Main Authors: Xueping He, Rong Hu, Peng Luo, Jie Gao, Wenjiang Yang, Jiaju Li, Youjiao Huang, Feng Han, Laijun Lai, Min Su
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-98443-5