The USP18 cysteine protease promotes HBV production independent of its protease activity

The USP18 cysteine protease promotes HBV production independent of its protease activity

Abstract Background Hepatitis B virus (HBV) infection remains as one of the major public health problems in the world. Type I interferon (IFN) plays an essential role in antiviral defense by induced expression of a few hundred interferon stimulated genes (ISGs), including ubiquitin-specific protease...

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Bibliographic Details
Main Authors: Yujia Li, Min Yao, Xiaoqiong Duan, Haiyan Ye, Shilin Li, Limin Chen, Chunhui Yang, Yongjun Chen
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Virology Journal
Subjects:
HBV
Interferon
USP18
Type I IFN signaling pathway
Persistent infection
Online Access:http://link.springer.com/article/10.1186/s12985-020-01304-2

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http://link.springer.com/article/10.1186/s12985-020-01304-2

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