Transcriptional drug repositioning and cheminformatics approach for differentiation therapy of leukaemia cells
Abstract Differentiation therapy is attracting increasing interest in cancer as it can be more specific than conventional chemotherapy approaches, and it has offered new treatment options for some cancer types, such as treating acute promyelocytic leukaemia (APL) by retinoic acid. However, there is...
Main Authors: | Yasaman KalantarMotamedi, Fatemeh Ejeian, Faezeh Sabouhi, Leila Bahmani, Alireza Shoaraye Nejati, Aditya Mukund Bhagwat, Ali Mohammad Ahadi, Azita Parvaneh Tafreshi, Mohammad Hossein Nasr-Esfahani, Andreas Bender |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-06-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-021-91629-x |
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