Coupled Hybrid Continuum-Discrete Model of Tumor Angiogenesis and Growth.

The processes governing tumor growth and angiogenesis are codependent. To study the relationship between them, we proposed a coupled hybrid continuum-discrete model. In this model, tumor cells, their microenvironment (extracellular matrixes, matrix-degrading enzymes, and tumor angiogenic factors), a...

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Bibliographic Details
Main Authors: Jie Lyu, Jinfeng Cao, Peiming Zhang, Yang Liu, Hongtao Cheng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5049767?pdf=render