Synthesis and Characterization of Covalently Crosslinked pH-Responsive Hyaluronic Acid Nanogels: Effect of Synthesis Parameters

Synthesis and Characterization of Covalently Crosslinked pH-Responsive Hyaluronic Acid Nanogels: Effect of Synthesis Parameters

Stable hyaluronic acid nanogels were obtained following the water-in-oil microemulsion method by covalent crosslinking with three biocompatible crosslinking agents: Divinyl sulfone, 1,4-butanediol diglycidyl ether (BDDE), and poly(ethylene glycol) bis(amine). All nanoparticles showed a pH-sensitive...

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Bibliographic Details
Main Authors: Sheila Maiz-Fernández, Leyre Pérez-Álvarez, Leire Ruiz-Rubio, Raúl Pérez González, Virginia Sáez-Martínez, Jesica Ruiz Pérez, José Luis Vilas-Vilela
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Polymers
Subjects:
hyaluronic acid
nanogels
divinyl sulfone
1,4-butanediol diglycidyl ether
poly(ethylene glycol) bis(amine)
Online Access:https://www.mdpi.com/2073-4360/11/4/742

Internet

https://www.mdpi.com/2073-4360/11/4/742

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